Lymphoma and azathioprine
نویسندگان
چکیده
منابع مشابه
Azathioprine shock.
Azathioprine has been used as an immunosuppressant for over 20 years in cancer chemotherapy, organ transplantation and diseases with confirmed or suspected immune mechanisms. A hypersensitivity reaction manifesting as fever, rash, myalgia and a neutrophil leucocytosis occurring about 2 weeks after exposure is well documented and has been confirmed by challenge testing. Hypotensive reactions are...
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Background and Objectives: Classic Hodgkin lymphoma (CHL), anaplastic large cell lymphoma (ALCL) and some cases of diffuse large B cell lymphoma (DLBCL) have overlapping morphologic features. Since they all represent distinct clinico-pathologic entities, we explored the differential diagnostic impact of immunophenotyping to discriminate between them. Materials and Methods:...
متن کاملCorticosteroids – Azathioprine
Fifteen years ago, classical immunosuppressive therapy was inconceivable without corticosteroids and azathioprine. A large number of transplantees administering these drugs had successful immunosuppression and good function of the graft over longer period of time. Nevertheless, side-effects of corticosteroids to cardiovascular system (hypertension, congestive heart failure, thrombophlebitis), t...
متن کاملLong Term Remission of a Primary Intracerebral Hodgkin Lymphoma in a Patient Previously Treated With Azathioprine
Primary central nervous system (CNS) lymphoma is a rare form of primary brain neoplasm, in which ninety percent of cases are diffuse large B-cell lymphoma. HL involving the CNS is a rare event happening most of them in the context of relapsed systemic disease [1,2]. Primary CNS-hodgkin lymphoma (CNS-HL) is very rare, occurring in less than 0.2% of all HL cases [3], and it has been poorly report...
متن کاملAzathioprine in dermatology.
Azathioprine is a synthetic purine analog derived from 6-mercaptopurine. It is a purine antagonist and its active metabolites act by disrupting the function of endogenous purines. It has a cytotoxic and immunosuppressive mechanism of action. It is used in dermatology for treatment of immunobullous diseases, generalized eczematous disorders and photodermatoses. There is an enzyme in the metaboli...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 1972
ISSN: 0004-3591,1529-0131
DOI: 10.1002/art.1780150516